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Characteristics of the discovery cohort.
| Characteristic | RSPO fusion positive | RNF43-mut | RNF43 and RSPO wild-type | |
|---|---|---|---|---|
| Total, no. (%) | 94 (1.3) | 443 (6.1) | 6,708 (92.6) | |
| Age, y | Median age | 61 | 69 | 62 |
| Range | 36–90 | 18–93 | 15–98 | |
| Sex, no. (%) | Female | 46 (49) | 263 (59) | 2,922 (44) |
| Male | 48 (51) | 180 (41) | 3,786 (56) | |
| Tumor location, no. (%) | Left | 23 (25) | 66 (15) | 2,156 (32) |
| Rectal | 29 (31) | 39 (9) | 1,640 (24) | |
| Right | 24 (26) | 232 (52) | 1,612 (24) | |
| Transverse | 8 (9) | 46 (10) | 293 (4) | |
| Unclear | 10 (11) | 60 (13.5) | 1,007 (15) |
