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. 2022 May 3;13:2400. doi: 10.1038/s41467-022-30003-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Histology and immunohistochemistry results, b Summary of non-synonymous mutations/Mb. c Relative contribution of mutational signatures from COSMIC. d Summary of genes showing recurrent mutation or fusion (altered in >5 patients) from WES and targeted RNA-seq data. CNA are shown in large blocks, coding alterations in small blocks. Alteration types are colored according to the legend. Samples are grouped by patient and site (primary or metastasis). Source data are provided in Supplementary Tables 4 and 5.