Table 3.
Currently active clinical trials with MNs for treating skin diseases.
| Type of skin disease | Type of MNs | Loading drugs | Status | Phase | NCT identifier |
|---|---|---|---|---|---|
| Psoriasis | DMN | Calcipotriol-betamethasone dipropionate ointment | Unknown | Not applicable | NCT02955576 |
| AGA | Solid MN | 5% Minoxidil | Unknown | Phase 1 | NCT02154503 |
| Scars | Fractional radiofrequency microneedling device | - | Completed | Not applicable | NCT03380845 |
| Scars | Solid MN | - | Unknown | Not applicable | NCT02025088 |
| Scars | Microneedling radiofrequency device | - | Completed | Not applicable | NCT02207738 |
| Acne vulgaris | Single radiofrequency microneedling device | - | Completed | Not applicable | NCT04213638 |
| Facial pigmentation | DMN | - | Enrolling by invitation | Not applicable | NCT04583852 |
| Facial pigmentation | Derma pen microneedling device | Trichloroacetic acid | Unknown | Not applicable | NCT03472235 |
| Hyperhidrosis | Fractional MN radiofrequency | Botulinum toxin type A | Completed | Not Applicable | NCT03054480 |
| Hyperhidrosis | Solid MN | Botulinum toxin type A | Completed | Phase 1 | NCT03203174 |
| Hyperhidrosis | Fractional MN radiofrequency | - | Completed | Not Applicable | NCT02823340 |
| Birch pollen allergy | Solid MN | - | Completed | Phase 1 | NCT01628484 |
| Actinic keratosis | Stainless steel MN | Aminolevulinic acid | Completed | Not applicable | NCT02594644 |
| Actinic keratosis | Solid MN | Aminolevulinic acid | Completed | Not applicable | NCT01812837 |
| Actinic keratosis | Solid MN | Aminolevulinic acid | Completed | Phase 2 | NCT02632110 |
Data obtained from http://www.clinicaltrials.gov.