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. 2022 Apr 20;13:868968. doi: 10.3389/fendo.2022.868968

Table 1.

Baseline characteristics of participants.

BMI (quartile) Q1 (11.21-24.10) Q2 (24.10-27.58) Q3 (27.58-31.90) Q4 (31.91-48.90) P value
N 4410 4441 4429 4433
Sex N (%) <0.001
Male 1714 (38.9%) 2359 (53.1%) 2397 (54.1%) 1923 (43.4%)
Female 2696 (61.1%) 2082 (46.9%) 2032 (45.9%) 2510 (56.6%)
Race, N (%) <0.001
White 3094 (70.2%) 3209 (72.3%) 3347 (75.6%) 3354 (75.7%)
Asian 243 (5.5%) 174 (3.9%) 77 (1.7%) 42 (0.9%)
African American 256 (5.8%) 246 (5.5%) 293 (6.6%) 408 (9.2%)
Unknown 817 (18.5%) 812 (18.3%) 712 (16.1%) 629 (14.2%)
Age range, N (%) <0.001
18-40 894 (20.3%) 716 (16.1%) 615 (13.9%) 713 (16.1%)
41-60 1722 (39.0%) 1785 (40.2%) 1807 (40.8%) 2042 (46.1%)
61-80 1633 (37.0%) 1747 (39.3%) 1849 (41.7%) 1613 (36.4%)
> 81 161 (3.7%) 193 (4.3%) 158 (3.6%) 65 (1.5%)
Serum sodium (Mean ± SD) 138.4 ± 3.3 138.6 ± 3.1 138.7 ± 3.1 138.9 ± 3.0 <0.001
Blood urea nitrogen (Mean ± SD) 16.8 ± 7.8 17.5 ± 7.8 17.8 ± 7.7 17.6 ± 8.5 <0.001
White blood cell count (Mean ± SD) 9.2 ± 4.4 9.4 ± 4.4 9.6 ± 4.4 9.7 ± 4.4 <0.001
Hematocrit (Mean ± SD) 39.3 ± 4.8 40.6 ± 4.7 40.9 ± 4.6 40.6 ± 4.6 <0.001
Platelet count (Mean ± SD) 250.7 ± 81.6 239.8 ± 74.0 238.7 ± 70.4 245.7 ± 73.5 <0.001
Duration of operation (Mean ± SD) 202.2 ± 124.7 209.2 ± 134.0 214.6 ± 131.6 227.6 ± 136.1 <0.001
Diabetes, N (%) <0.001
No 4163 (94.4%) 4058 (91.4%) 3897 (88.0%) 3547 (80.0%)
Yes (Noninsulin-dependent) 162 (3.7%) 247 (5.6%) 336 (7.6%) 546 (12.3%)
Yes (Insulin-dependent) 85 (1.9%) 136 (3.1%) 196 (4.4%) 340 (7.7%)
Smoking status, N (%) <0.001
No 3261 (73.9%) 3624 (81.6%) 3661 (82.7%) 3734 (84.2%)
Yes 1149 (26.1%) 817 (18.4%) 768 (17.3%) 699 (15.8%)
Ventilator dependence, N (%) 0.067
No 4362 (98.9%) 4396 (99.0%) 4372 (98.7%) 4401 (99.3%)
Yes 48 (1.1%) 45 (1.0%) 57 (1.3%) 32 (0.7%)
Severe COPD, N (%) <0.001
No 4120 (93.4%) 4285 (96.5%) 4251 (96.0%) 4264 (96.2%)
Yes 290 (6.6%) 156 (3.5%) 178 (4.0%) 169 (3.8%)
Congestive heart failure, N (%) 0.023
No 4396 (99.7%) 4432 (99.8%) 4420 (99.8%) 4410 (99.5%)
Yes 14 (0.3%) 9 (0.2%) 9 (0.2%) 23 (0.5%)
Hypertension, N (%) <0.001
No 3330 (75.5%) 2934 (66.1%) 2535 (57.2%) 2177 (49.1%)
Yes 1080 (24.5%) 1507 (33.9%) 1894 (42.8%) 2256 (50.9%)
Renal failure, N (%) 0.057
No 4409 (100.0%) 4441 (100.0%) 4424 (99.9%) 4428 (99.9%)
Yes 1 (0.0%) 0 (0.0%) 5 (0.1%) 5 (0.1%)
Disseminated cancer, N (%) <0.001
No 3146 (71.3%) 3542 (79.8%) 3572 (80.7%) 3673 (82.9%)
Yes 1264 (28.7%) 899 (20.2%) 857 (19.3%) 760 (17.1%)
Open wound infection, N (%) 0.221
No 4369 (99.1%) 4408 (99.3%) 4400 (99.3%) 4388 (99.0%)
Yes 41 (0.9%) 33 (0.7%) 29 (0.7%) 45 (1.0%)
Steroid use, N (%) 0.058
No 3741 (84.8%) 3797 (85.5%) 3708 (83.7%) 3792 (85.5%)
Yes 669 (15.2%) 644 (14.5%) 721 (16.3%) 641 (14.5%)
Preoperation transfusions, N (%) 0.600
No 4391 (99.6%) 4427 (99.7%) 4417 (99.7%) 4419 (99.7%)
Yes 19 (0.4%) 14 (0.3%) 12 (0.3%) 14 (0.3%)
Emergency case, N (%) <0.001
No 4131 (93.7%) 4218 (95.0%) 4201 (94.9%) 4274 (96.4%)
Yes 279 (6.3%) 223 (5.0%) 228 (5.1%) 159 (3.6%)
30 day mortality events, N (%) 117 (2.65%) 91 (2.05%) 115 (2.60%) 100 (2.26%) 0.021