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Anti-proliferative activities of compounds 3d and erlotinib against drug-resistant cancer cell lines.
| IC50(μM) | |||||
|---|---|---|---|---|---|
| KYSE70TR | KYSE410TR | KYSE450TR | H1650TR | HCC827GR | |
| 3d | 7.17 ± 0.73 | 7.91 ± 0.61 | 10.02 ± 0.75 | 5.76 ± 0.33 | 2.38 ± 0.17 |
| Erlotinib | >20 | >20 | >20 | >20 | >20 |
