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. 2022 Apr 20;13:850066. doi: 10.3389/fphar.2022.850066

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Copyright © 2022 Abdel-latif, Heeba, Hassanin, Waz and Amin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative Western blot analysis of the effect of NaHS and PAG on hepatic TLR4 (A) and p-JNK (B) protein expressions in CP-induced hepatotoxicity in rats, showing protein bands of each group (upper panel) and graphs present their densitometric analysis (lower panel). Data are represented as mean ± SEM. *,+,° are significantly different from control, CP and NaHS groups, respectively, where n = 6 and p<0.05. CP; cyclophosphamide, PAG; DL-propargylglycine, TLR4; Toll-like receptor4, p-JNK; phosphorylated Jun N-terminal kinase.