Uncoated K2-nanoliposomes | Chitosan-coated K2-nanoliposomes | |||
---|---|---|---|---|
Time | t = 0 | t = 1 | t = 0 | t = 1 |
Size (nm) ± SD | 144.8 ± 32.7 | 95.6 ± 33.0 | 278.5 ± 105.0 | 324.7 ± 122.0 |
Z-Average (nm) ± SD | 289.1 ± 5.6 | 322.9 ± 6.85 | 930.1 ± 59.5 | 726.2 ± 35.0 |
PDI ± SD | 0.31 ± 0.02 | 0.37 ± 0.03 | 0.71 ± 0.09 | 0.50 ± 0.09 |
Zeta potential (mV) ± SD | −36.2 ± 0.3 | −36.6 ± 3.0 | −23.7 ± 1.3 | −21.1 ± 0.6 |
EE (%) ± SD | 94.7 ± 0.8 | 93.8 ± 0.4 | 98.2 ± 0.6 | 95.2 ± 0.2 |
Mucoadhesivity ± SD | 0.0 ± 0.0 | 4.0 ± 5.4 | 79.5 ± 1.2 | 77.8 ± 0.4 |