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. 2019 Jun 25;9(34):19800–19812. doi: 10.1039/c9ra03022k
Uncoated D3-nanoliposomes Chitosan-coated D3-nanoliposomes
Time t = 0 t = 1 t = 0 t = 1
Size (nm) ± SD 87.4 ± 17.3 117.0 ± 42.6 235.1 ± 29.3 211.1 ± 76.6
Z-Average (nm) ±S D 344.0 ± 61.9 503.0 ± 10.9 434.0 ± 31.5 393.9 ± 11.7
PDI ± SD 0.40 ± 0.07 0.50 ± 0.03 0.25 ± 0.05 0.29 ± 0.04
Zeta potential (mV) ± SD −38.5 ± 1.6 −37.2 ± 2.1 −20.2 ± 0.5 −18.9 ± 1.5
EE (%) ± SD 88.4 ± 2.5 87.3 ± 0.7 98.3 ± 0.5 98.4 ± 0.1
Mucoadhesivity ± SD 0.0 ± 0.0 3.2 ± 7.7 86.3 ± 1.1 88.5 ± 3.5