Uncoated D3-nanoliposomes | Chitosan-coated D3-nanoliposomes | |||
---|---|---|---|---|
Time | t = 0 | t = 1 | t = 0 | t = 1 |
Size (nm) ± SD | 87.4 ± 17.3 | 117.0 ± 42.6 | 235.1 ± 29.3 | 211.1 ± 76.6 |
Z-Average (nm) ±S D | 344.0 ± 61.9 | 503.0 ± 10.9 | 434.0 ± 31.5 | 393.9 ± 11.7 |
PDI ± SD | 0.40 ± 0.07 | 0.50 ± 0.03 | 0.25 ± 0.05 | 0.29 ± 0.04 |
Zeta potential (mV) ± SD | −38.5 ± 1.6 | −37.2 ± 2.1 | −20.2 ± 0.5 | −18.9 ± 1.5 |
EE (%) ± SD | 88.4 ± 2.5 | 87.3 ± 0.7 | 98.3 ± 0.5 | 98.4 ± 0.1 |
Mucoadhesivity ± SD | 0.0 ± 0.0 | 3.2 ± 7.7 | 86.3 ± 1.1 | 88.5 ± 3.5 |