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. 2019 Jun 25;9(34):19855–19868. doi: 10.1039/c9ra03640g

Inhibitory effects of 6, 10, and 11 toward a panel of liver cancer cell lines.

IC50 (μM)
6 10 11
Huh-7 1.54 ± 0.08 1.90 ± 0.18 1.40 ± 0.09
HepG2 1.31 ± 0.11 1.52 ± 0.13 1.20 ± 0.10
SMMC-7721 2.70 ± 0.12 3.39 ± 0.15 3.19 ± 0.24
Hep3b 1.38 ± 0.09 0.63 ± 0.05 1.29 ± 0.12
SUN475 1.10 ± 0.06 1.52 ± 0.09 1.11 ± 0.07
SUN449 1.92 ± 0.12 1.90 ± 0.11 1.47 ± 0.11
Sk-hep1 0.66 ± 0.05 0.98 ± 0.04 0.42 ± 0.05