Table 2.

Some list of MN patch clinical trials recorded up to January 2022 (available at https://clinicaltrials.gov/us).

Status	Object	Phase
Enrolling by invitation	Brightening cutaneous tissue using MN in individuals with solar Lentigines	Not Applicable
Completed	Local delivery of Lidocaine for oral anesthesia using MN	Phase I
Completed	Vaccination against viruses in healthy infants/young children using MN	Not Applicable
Completed	Diabetes diagnosis and glucose monitoring using MN	Not Applicable
Unknown	MN for the treatment of psoriatic plaques	Not Applicable
Suspended	Pilocarpine microneedles for sweat induction in cystic fibrosis patients using MN	Not Applicable
Completed	Vaccination against influenza	Phase I
Recruiting	Vaccination against measles and rubella	Phases I and II
Recruiting	Efficacy of transdermal microneedle patch for topical anesthesia enhancement in pediatric thalassemia patients	Phase II
Recruiting	MN for delivery of Doxorubicin in patients with cutaneous T-cell Lymphoma	Phase I
Completed	Dose-limiting toxicity and maximum tolerated dose of MN containing Doxorubicin in basal cell carcinoma	Phase I
Recruiting	Evaluation of cutaneous micropores after application of MN	Not Applicable
Completed	Physiological study to determine the allergic skin activity after different skin preparation using MN	Phase I
Completed	Pain and safety of microneedles in oral cavity	Not Applicable
Completed	Minimally invasive sensing of beta-lactam antibiotics	Phase I
Unknown	Microneedle and trichloroacetic acid in treatment of melasma	Not Applicable
Recruiting	Microneedles for diagnosis of latent tuberculosis	Not Applicable
Unknown	Microneedle radiofrequency for moderate-to-severe acne vulgaris	Not Applicable

MN: microneedle patch.