Table 1.
Patient characteristics at baseline, treatments, and outcomes. Values are median (interquartile range) unless stated otherwise
| Characteristics | Estimate (n=7345) |
|---|---|
| No (%) women | 2265 (30.8) |
| Age (years) | 59 (49-68) |
| SOFA score | 4 (3-6) |
| APACHE II score | 14 (10-18) |
| Ventilation variables at baseline: | |
| Tidal volume (mL/kg predicted bodyweight) | 6.4 (5.8-7.1) |
| FiO2 (%) | 60 (49-76) |
| Positive end expiratory pressure (cmH2O) | 10 (8-12) |
| Airway plateau pressure (cmH2O) | 22 (20-25) |
| Respiratory rate per minute | 24 (20-28) |
| Gas exchange at baseline: | |
| PaO2/FiO2 ratio (mm Hg) | 130 (88-193) |
| PaO2 (mm Hg) | 79 (64-100) |
| SaO2 (%) | 94 (91-96) |
| Arterial pH | 7.41 (7.35-7.45) |
| PaCO2 (mm Hg) | 39 (34-47) |
| Serum bicarbonate (mmol/L) | 24 (22-27) |
| Lactate (mmol/L) | 1.4 (1.1-1.9) |
| No (%) of specific treatments recorded for at least one day during follow-up: | |
| Prone position | 1117 (15.2) |
| Neuromuscular blockade agent | 1707 (23.2) |
| Inhaled nitric oxide | 72 (1.0) |
| Vasoactive drugs | 1590 (21.6) |
| Renal replacement therapy | 738 (10.0) |
| Corticosteroids | 2961 (40.3) |
SOFA=sequential organ failure assessment; APACHE=acute physiology and chronic health evaluation; FiO2=fraction of inspiratory oxygen; PaO2=arterial partial pressure of oxygen; SaO2=arterial oxygen saturation; PaCO2=arterial partial pressure of carbon dioxide.