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. 2022 Apr 20;13:851242. doi: 10.3389/fphar.2022.851242

FIGURE 2.

FIGURE 2

3D plots of the results derived from the central composite design for size (A), polydispersity index [PDI; (B)], encapsulation efficacy [EE; (C)] and release (D) as a function of the parameters (concentrations of Span® 60 and cholesterol).