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. 2022 Apr 20;13:820086. doi: 10.3389/fphar.2022.820086

TABLE 6.

The top 20 keywords of COPD drugs-related studies that were published from 1980 to 2021.

Rank Frequency Centrality Key words
1 1,312 0.04 COPD
2 717 0.03 Obstructive pulmonary disease
3 286 0.02 Exacerbation
4 244 0.03 Tiotropium
5 206 0.06 Mortality
6 192 0.05 Management
7 176 0.03 Therapy
8 173 0.05 Double blind
9 170 0.12 Efficacy
10 169 0.01 Lung function
11 155 0.02 Inflammation
12 147 0.02 Risk
13 143 0.01 Salmeterol
14 136 0.01 Safety
15 131 0.11 Disease
16 131 0.05 Prevalence
17 115 0.03 Bronchodilator
18 105 0.03 Quality of life
19 102 0.04 Chronic bronchiti
20 101 0.03 Acute exacerbation