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. 2022 Apr 20;13:887681. doi: 10.3389/fimmu.2022.887681

Figure 4.

Figure 4

SM + M stimulated IL-17A production in CD4+CD25highCD127low Treg cells from spleen and lung. (A) Representative flow cytometry gating and quantitative bar graph show the IL-17A and IL-10 production in splenocytes upon treatments. Dot plot indicate the frequency of IL-10 and IL-17A producing cells in CD3+CD4+ T cells and Treg cells. (B) Representative flow cytometry gating and quantitative bar graph show the IL-17A and IL-10 production in lung cells upon treatments. Dot plot indicate the frequency of IL-10 and IL-17A producing cells in CD3+CD4+ T cells and Treg cells. (n = 8) (T-test, *p < 0.05, **p < 0.01,***p < 0.001, * in black represents the difference between SM, M or SM+M and NS control, * in red represents the difference between SM+M and SM or M).