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. 2022 Apr 20;13:887681. doi: 10.3389/fimmu.2022.887681

Table 1.

CD4+CD25highCD127low regulatory T cells (Treg) RNA-Seq experiments led to identification of numerous differentially expressed genes (DEGs) in Treg in four groups of mice (n = 2).

Comparison of groups Genes annotated Genes with P.Value <0.05 Genes with |log2FC| >1
SM vs NS 19121 1105 648 ↑ 211
↓ 437
M vs NS 1171 902 ↑ 233
↓ 669
SM+M vs NS 2539 1630 ↑ 630
↓ 1000
SM+M vs M 2196 1507 ↑ 743
↓ 764
SM+M vs SM 912 710 ↑ 349
↓ 361

To determine the various stimulation effects on Treg transcriptome, the comparisons were made in five pairs: i) SM versus NS; ii) M versus NS; iii) SM_M versus NS; iv) SM_M versus M; and v) SM_M versus SM.

↑means up-regulated; ↓means down-regulated.