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. 2022 Apr 20;13:874108. doi: 10.3389/fimmu.2022.874108

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Copyright © 2022 Alexandre, Bohelay, Gille, Le Roux-Villet, Soued, Morin, Caux, Grootenboer-Mignot and Prost-Squarcioni

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dramatic improvement of daily blister count, pruritus visual analog score (PVAS) and urticaria score between baseline (blue) and the 15^th day after omalizumab therapy (purple). Data are presented as box and whisker plots showing extreme values, interquartile ranges, and medians. **p < 0.01, ***p < 0.001 (Wilcoxon signed–rank test).