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. 2019 Jul 2;9(36):20513–20517. doi: 10.1039/c9ra04034j

The summary of IC50 and CI index. ★ represents IC50 based on Pt. ◆ represents IC50 based on Dox. N.A. represents not applicable.

IC50 CI50
A2780 A2780DDP A2780 A2780DDP
Pt 9.41 31.03 N.A. N.A.
Dox 1.08 1.10 N.A. N.A.
Pt + Dox 1.22★/0.75◆ 0.99★/0.61◆ 0.87 0.59
NPs (Pt(iv) + CAD) 1.38★/0.72◆ 0.99★/0.60◆ 0.55 0.21
NPs (Pt(iv)) 3.80 9.61 N.A. N.A.
NPs (CAD) 3.84 5.7 N.A. N.A.