Fig. 5. Porcupine plot depicting the dominant motions in PS2-γ-secretase obtained from the first two eigenvectors (EV1 and EV2) by PCA. (A) The movement of EV1 of simulation 1 (B). EV1 of simulation 2. (C) EV1 of simulation 3. (D) EV2 of simulation 1 (E) EV2 of simulation 2. (F) EV2 of simulation 3. Red needles show the direction (arrows) and amplitude of motion (the length). The different subunits are colored (Nicastrin: green; PS2-NTF: cyan; PS2-CTF: magenta; APH1: mellow; PEN2: tint wheat).
