Table 5.
Univariate and multivariate analysis of predictor of symptomatic hypotension
| Variable |
Univariate analysis OR (95% CI), P‐value |
Multivariate analysis OR (95% CI), P‐value |
|---|---|---|
| Patients, no. | 106 | |
| Age, years | 1.02 (0.98–1.07), P = 0.33 | — |
| Male sex, no. (%) | 1.92 (0.51–7.19), P = 0.34 | — |
| CV risk factors | ||
| Hypertension | 0.74 (0.23–2.35), P = 0.61 | — |
| Diabetes | 0.74 (0.29–1.91), P = 0.54 | — |
| Physical features | ||
| Systolic BP (mmHg) | 0.99 (0.96–1.02), P = 0.36 | — |
| Diastolic BP (mmHg) | 0.96 (0.91–1.02), P = 0.16 | — |
| Pulse pressure (mmHg) | 1.00 (0.96–1.04), P = 0.96 | — |
| Heart rate (b.p.m.) | 1.00 (0.96–1.04), P = 0.84 | — |
| BMI (kg/m2) | 1.02 (0.99–1.05), P = 0.29 | — |
| Aetiology of HF | ||
| Ischaemic aetiology | 1.10 (0.41–2.96), P = 0.86 | — |
| Baseline laboratory analysis | ||
| Serum sodium (mg/mL) | 0.90 (0.79–1.04), P = 0.15 | — |
| Serum potassium (mg/mL) | 1.26 (0.56–2.84), P = 0.58 | — |
| eGFR (mL/min/1.72 m2) | 0.99 (0.97–1.02), P = 0.61 | — |
| Haemoglobin (g/dL) | 0.78 (0.59–1.04), P = 0.096 | 0.80 (0.59–1.09), P = 0.15 |
| lnBNP (pg/mL) | 1.02 (0.63–1.65), P = 0.93 | — |
| NYHA Class III | 3.00 (1.20–7.53), P = 0.019 | 2.65 (1.07–6.5), P = 0.034 |
| Atrial fibrillation/flutter at baseline ECG | 0.42 (0.13–1.36), P = 0.15 | — |
| Paced rhythm at baseline ECG | 1.70 (0.65–4.43), P = 0.28 | — |
| Echocardiogram | ||
| LVEDVi (mL/m2) | 1.01 (1.00–1.02), P = 0.28 | — |
| Ejection fraction (%) | 0.89 (0.83–0.97), P = 0.005 | 0.92 (0.85–1.00), P = 0.053 |
| SVi (per 5 mL/m2) | 0.65 (0.46–0.91), P = 0.012 | 0.63 (0.44–0.90), P = 0.012 |
| Cardiac index (mL/min/m2) | 1.00 (1.00–1.00), P = 0.033 | — |
| Flow rate (mL/min) | 0.99 (0.98–1.00), P = 0.021 | — |
| PAPs (mmHg) | 0.96 (0.90–1.03), P = 0.24 | — |
| Diastolic dysfunction (Grade III) | 0.86 (0.30–2.51), P = 0.79 | — |
| Loop diuretics preventive reduction | 1.24 (0.48–3.19), P = 0.65 | — |
BMI, body mass index; BNP, brain natriuretic peptide; BP, blood pressure; CI, confidence interval; CV, cardiovascular; ECG, electrocardiogram; eGFR, estimated glomerular filtration rate; HF, heart failure; LVEDVi, left ventricular end‐diastolic volume index; NYHA, New York Heart Association; OR, odds ratio; PAPs, pulmonary artery pressures; SVi, stroke volume index. P‐values < 0.05 are reported in bold.