Table 2.
Baseline echocardiographic characteristics
| Overall population (n = 807) | TAPSE/PASP ratio <0.45 mm/mmHg (n = 360) | TAPSE/PASP ratio ≥0.45 mm/mmHg (n = 447) | P value | |
|---|---|---|---|---|
| LVEDV, mL | 187 (146–243) | 196 (150–245) | 183 (144–243) | 0.086 |
| LVESV, mL | 137 (99–178) | 144 (105–187) | 129 (96–172) | 0.004 |
| LVEF, % | 27.8 (±8.3) | 26.1 (±8.0) | 29.2 (±8.3) | <0.001 |
| LAVi, mL/m2 | 44.2 (±20.2) | 49.8 (±20.2) | 39.7 (±19.1) | <0.001 |
| Moderate to severe MR (%) | 314 (42.7%) | 176 (56.6%) | 138 (32.5%) | <0.001 |
| RVEDA, cm2 | 22.5 (±7.1) | 24.5 (±7.9) | 20.9 (±5.8) | <0.001 |
| RVESA, cm2 | 14.6 (±6.3) | 17.0 (±7.0) | 12.7 (±4.9) | <0.001 |
| RVFAC, % | 36.6 (±12.9) | 31.8 (±12.4) | 40.6 (±11.9) | <0.001 |
| RA area, cm2 | 18.5 (14.6–23.9) | 20.7 (16.7–25.9) | 16.8 (13.6–21.7) | <0.001 |
| TAPSE, mm | 16.1 (±4.8) | 13 (±4.0) | 18 (±4.0) | <0.001 |
| TR velocity, m/s | 2.58 (±0.58) | 2.93 (±0.52) | 2.29 (±0.45) | <0.001 |
| PASP, mmHg | 35 (± 14) | 44 (±14) | 27 (± 8) | <0.001 |
| Moderate to severe TR (%) | 212 (28.0%) | 154 (45.8%) | 58 (13.8%) | <0.001 |
EDA, end‐diastolic area; EDV, end‐diastolic volume; EF, ejection fraction; ESA, end‐systolic area; ESV, end‐systolic volume; FAC, fractional area change; LAVi, left atrial volume index; LV, left ventricular; MR, mitral regurgitation; PASP, pulmonary artery systolic pressure; RA, right atrial; RV, right ventricular; TAPSE, tricuspid annular plane systolic excursion; TR, tricuspid regurgitation.