Figure 1.
Systemic microbial translocation and distinct circulating microbial profiles in INRs. Plasma levels of LPS (A), sCD14 (B), and bacterial 16S rDNA (C) from the three study groups. (D) The Gini Simpson diversity index (α-diversity) was used to compare the diversity of the plasma-circulating microbial community within INRs and IRs or healthy controls. (E) PCoA was conducted based on the unweighted UniFrac distance to determine the beta diversity of the plasma microbial community. One-way ANOVA was used, followed by Tukey's post hoc test. The statistical significance of the beta diversity was tested using the Multivariate Welch t-test. ** p < 0.01, *** p < 0.001, **** p < 0.0001.