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. 2022 Apr 24;18(7):3082–3101. doi: 10.7150/ijbs.70524

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Gastric cancer has a high expression of LAMC1 and are prone to colonize to adipocyte-rich peritoneum. (A) (a) HE (b) Masson (c) Oil Red O staining results of primary lesion and peritoneal metastasis lesion were shown. (B) The clustering heatmap of significant proteins. (C) Gene function classification. (D) Clustering heatmap of extracellular matrix organization proteins. (E) Analysis of single-cell sequencing data. (F) The correlation between LAMC1 and Perilipin-1 was analyzed by immunofluorescence staining in peritoneal metastasis samples. (G) Western blots result for analyzing LAMC1 expression in patients' tissue specimen with or without peritoneal metastasis. (H) Immunohistochemistry for analyzing LAMC1 expression in patients' tissue specimen with or without peritoneal metastasis.