Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 11;18(7):2898–2913. doi: 10.7150/ijbs.70975

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

MHO7 activated the antitumor immune response in mice. (A) KEGG pathway enrichment of DEGs was analyzed by RNA-seq in 4T1 tumor tissue. (B) GO enrichment of DEGs was analyzed by RNA-seq in 4T1 tumor tissue. (C) Percentages of CD11C⁺/CD86⁺ DCs were measured by flow cytometry in spleens. (D) Percentages of CD11C⁺/ MHC II⁺ DCs were measured by flow cytometry in spleens. (E) Percentages of CD3⁺/CD8⁺ T cells were measured by flow cytometry in spleens. (F) Percentages of CD4⁺/FOXP3⁺ T cells were measured by flow cytometry in spleens. (n=6) The level of (G) IFN-γ, (H) TNF-α, (I) IL-1β, and (J) IL-6 were measured by ELISA in the serum on day 7 after treatment. Data was presented as mean ± SEM. *P <0.05; **P < 0.01; ***P <0.001; and ****P < 0.0001; ns=no significance.