Fig. 4. Knockdown of CRNDE regulated apoptosis and apoptosis-related proteins expression of TSCC cells. Flow cytometric analysis for cell apoptosis (A) and (B), caspase-3 activity assay for caspase-3 activity (C), Western blot for Bcl-2, cleaved caspase-3 and Bax levels (D) and (E) in si-NC- or si-CRNDE-transfected Cal27 and SCC cells. **P < 0.01 or ***P < 0.001.
