Fig. 5. CRNDE regulated PI3K/AKT/mTOR pathway in TSCC cells. The expression levels of PI3K, mTOR, AKT, p-PI3K, p-mTOR and p-AKT were measured by Western blot in pcDNA-, pcDNA-CRNDE-, si-NC- or si-CRNDE-transfected Cal27 cells (A) and (B), and SCC4 cells (C) and (D). **P < 0.01 or ***P < 0.001.