Percentage of inhibition (% I) at 150 μg mL−1, the IC50 value (μg mL−1) and the inhibitory mode of W. filifera seeds extracts against xanthine oxidasea.
Extracts | % I | IC50 | Inhibitory mode |
---|---|---|---|
EEG | 52.4 ± 0.8 | 95.8 ± 5.9* | Mixed |
EES | 63.9 ± 0.1 | 87.0 ± 0.5* | Mixed |
MEG | 72.8 ± 0.3 | 75.2 ± 17.0* | Mixed |
MES | 74.6 ± 0.2 | 76.1 ± 5.2* | Mixed |
AEG | 36.7 ± 0.1 | n.d | n.d |
AES | 37.7 ± 0.1 | n.d | n.d |
Allopurinol | 2.0 ± 0.4 |
n.d: not determined because inhibition at the highest screened concentration (150 μg mL−1) was less than 40%. Values were expressed as mean ± SD (n = 3). Values of the IC50 for alcoholic extracts compared to allopurinol were significantly different (p < 0.05).