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. 2022 Mar 28;13(7):2040–2049. doi: 10.7150/jca.65167

Figure 1.

Figure 1

Low expression of miR-1247-3p was found in lung adenocarcinoma tissues. A:162 pairs from adenocarcinoma tissues of lung were examined and miR-1247-3p expression was observed using qRT-PCR. Unlike adjacent normal tissue cells, a reduced miR-1247-3p expression was found in these tissues. B: Among these 162 pairs, 113 tumor tissues showed low and 7 showed high expressions of miR-1247-3p. C: miR-1247-3p expression in T1+T2 vs T3+T4 in adenocarcinoma tissues of lung was observed. Results revealed a higher expression in T1+T2 as compared to T3+T4. D: The expression of miR-1247-3p was also detected in adenocarcinoma tissue of lung with or without lymph nodes tumors. E: The expression of miR-1247-3p was also detected in adenocarcinoma tissue of lung showing distant metastasis and also in the tissues without showing any symptom of distant metastasis. F: miR-1247-3p expression was also detected in normal epithelial cells of lung and cell lines of adenocarcinoma tissue cells. The expression was higher in normal epithelial cells of lung. ***p<0.001 compared with group normal, T1+T2, N0, M0, or HNBE. Lentiviruses-inhibitor normal control (LV-INC), Lentiviruses-inhibitor (LV-inhibitor), Lentiviruses-mimics normal control (LV-mNC), Lentiviruses- mimics (LV-mimics). The experiments were repeated at least 3 independent times.