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. 2022 Mar 28;13(7):2040–2049. doi: 10.7150/jca.65167

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Chemotherapy resistance of adenocarcinoma cells of lung was inhibited by miR-1247-3p. A: When treated with Docetaxel, in the cell lines of A549, the mimics group was found to be in reduced survival rate as compared to the group of LV-mNC. B: When administered Doxorubicin, in the cell lines of A549, the mimics group was found to be in reduced survival rate when comparing with the LV-mNC group. C: When treated with Gefitinib, in A549 cells lines, LV-mimics group was lower in survival rate than LV-mNC group. D: In the cell lines of NCI-H1395, when treated with Docetaxel, a higher survival rate of inhibitor group was observed as compared to LV-INC group. E: In NCI-H1395 cell lines, when treated with Doxorubicin, LV-inhibitor group was increased in survival rate than LV-INC group. F: In NCI-H1395 cell lines, when treated with Gefitinib, a higher survival rate of inhibitor group was observed as compared to group of LV-INC. ***p<0.001 compared with group LV-INC or LV-mNC. Lentiviruses-inhibitor normal control (LV-INC), Lentiviruses-inhibitor (LV-inhibitor), Lentiviruses-mimics normal control (LV-mNC), Lentiviruses- mimics (LV-mimics). The experiments were repeated at least 3 independent times.