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. 2022 Feb 22;10(2):e003663. doi: 10.1136/jitc-2021-003663

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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YTHDF1 is overexpressed in GC and its expression is associated with poor survival of patients with GC. (A) Comparison of YTHDF1 mRNA levels between paired GC tumor tissues and adjacent normal tissues from our GC cohort 1 (n=101) and YTHDF1 mRNA expression predicts worse survival using Gehan-Breslow-Wilcoxon test. (B) Comparison of YTHDF1 mRNA levels in TCGA GC cohort (overall cohort: adjacent normal: n=32, tumor: n=375; paired samples: n=27). (C) YTHDF1 protein expression predicts worse survival in patients with GC using Gehan-Breslow-Wilcoxon test. Representative images of TMA in our cohort 2. GC, gastric cancer; TMA, tissue microarray.