Oxidative indicators modulation after LOP caused acute-constipation and corrective action of ACCEa.
| MDA (10−3 nmol mg−1 proteins) | –SH (nmol mg−1 proteins) | Carbonylated-proteins (μmol mg−1 proteins) | SOD (10−3 U mg−1 proteins) | CAT (10−3 mol min−1 mg−1 proteins) | ||
|---|---|---|---|---|---|---|
| NaCl | (5 mL kg−1) | 30.45 ± 3.45 | 77.22 ± 6.45 | 19.54 ± 1.523 | 138.44 ± 7.30 | 296.67 ± 11.11 |
| LOP | (5 mg kg−1) | 95.23 ± 5.56* | 37.00 ± 2.77* | 39.29 ± 3.91* | 79.18 ± 5.91* | 188.48 ± 9.00* |
| ACCE | (150 mg kg−1) | 64.34 ± 4.17*# | 47.24 ± 4.21*# | 32.43 ± 2.33*# | 84.11 ± 6.33* | 227.81 ± 8.05*# |
| (300 mg kg−1) | 29.45 ± 4.22# | 68.43 ± 4.50*# | 20.28 ± 0.94# | 111.56 ± 5.12# | 279.98 ± 10.77# | |
a
ACCE/LOP actions reflected by indicated oxidative stress parameters and assessed in healthy and constipated rats. Data are expressed as mean ± standard error (n = 7); *p < 0.05 versus control group, #p < 0.05 versus LOP-group.