Table 1.
Anthropometric and laboratory data of PCOS patients and controls including subgroups with and without IBS symptoms. Data are presented as the median and interquartile range (IQR) or number (percentage).
Variable | PCOS patients (n = 133) | Controls (CON) (n = 72) | IBS-PCOS vs IBS-CON (P) | ||||
---|---|---|---|---|---|---|---|
IBS-PCOS (n = 32) | non-IBS-PCOS (n = 101) | P | IBS-CON (n = 15) | non-IBS-CON (n = 57) | P | ||
Age (years) | 26.96 (5.71) | 24.42 (5.00) | 0.01 | 28.25 (12.08) | 24.83 (8.17) | 0.21 | 0.88 |
BMI (kg/m2) | 23.57 (12.76) | 24.21 (6.97) | 0.58 | 22.04 (9.89) | 24.20 (6.93) | 0.99 | 0.28 |
WC (cm) | 79.50 (31.00) | 82.00 (18.00) | 0.58 | 78.00 (25.00) | 80. 00 (18.00) | 0.74 | 0.72 |
WHtR | 0.48 (0.18) | 0.48 (0.11) | 0.61 | 0.48 (0.20) | 0.47 (0.09) | 0.54 | 0.99 |
AMH (pg/mL) | 47.48 (31.33) | 52.38 (47.84) | 0.54 | 20.35 (17.58) | 27.10 (9.07) | 0.83 | 0.005 |
Glucose (mg/dL) | 89.00 (8.00) | 88.00 (10.00) | 0.39 | 86.00 (10.00) | 88.50 (8.00) | 0.49 | 0.24 |
Insulin (mIU/mL) | 8.77 (10.33) | 9.54 (7.16) | 0.86 | 9.77 (3.98) | 8.07 (7.31) | 0.30 | 0.99 |
HOMA-IR | 1.92 (2.08) | 2.19 (1.69) | 0.81 | 1.98 (0.89) | 1.80 (1.60) | 0.35 | 0.92 |
TC (mg/dL) | 170.00 (31.00) | 171.00 (40.00) | 0.86 | 180.00 (55.00) | 164.00 (35.00) | 0.37 | 0.57 |
TG (mg/dL) | 82.00 (59.00) | 70.00 (50.00) | 0.20 | 71.00 (61.00) | 81.00 (38.00) | 0.87 | 0.52 |
HDL-C (mg/dL) | 59.00 (25.00) | 61.00 (20.00) | 0.41 | 63.00 (35.00) | 65.00 (25.00) | 0.93 | 0.23 |
LDL-C (mg/dL) | 92.20 (28.50) | 90.60 (35.00) | 0.77 | 77.20 (43.70) | 83.55 (35.35) | 0.61 | 0.38 |
TSH (µU/mL) | 1.80 (1.34) | 2.14 (1.32) | 0.02 | 2.18 (0.97) | 2.24 (1.25) | 0.34 | 0.31 |
FSH (mU/mL) | 5.75 (2.20) | 5.80 (2.10) | 0.86 | 4.65 (3.80) | 5.50 (3.10) | 0.28 | 0.28 |
LH (mU/mL) | 7.05 (6.30) | 8.45 (8.60) | 0.11 | 5.10 (2.55) | 6.50 (5.40) | 0.37 | 0.19 |
DHEAS (µg/dL) | 331.00 (218.00) | 319.00 (181.00) | 0.55 | 226.00 (123.00) | 256 .00 (110.00) | 0.20 | 0.03 |
T (nmol/L) | 1.46 (1.40) | 1.75 (1.00) | 0.44 | 1.20 (0.80) | 1.20 (0.80) | 0.68 | 0.31 |
FTI (%) | 3.37 (3.44) | 3.37 (2.58) | 0.59 | 1.52 (1.83) | 1.75 (2.66) | 0.98 | 0.16 |
E2 (pg/mL) | 40.00 (39.00) | 44.00 (42.00) | 0.18 | 87.00 (70.00) | 52.00 (75.50) | 0.79 | 0.29 |
SHBG (nmol/L) | 50.90 (48.00) | 50.95 (32.95) | 0.83 | 69.50 (106.00) | 56.40 (26.90) | 0.44 | 0.19 |
MS presence | 9/31 (29.0%) | 10/97 (10.3%) | 0.01 | 1/14 (7.1%) | 3/51 (5.9%) | 0.862 | 0.10 |
AMH, anti-Müllerian hormone; DHEAS, DHEA sulfate; E2, estradiol; FSH, follicle-stimulating hormone; FTI, free testosterone index; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment for insulin resistance; IBS-CON, controls with irritable bowel syndrome; IBS-PCOS, polycystic ovary syndrome patients with irritable bowel syndrome; LDL-C, low-density lipoprotein cholesterol; LH, luteinizing hormone; MS, metabolic syndrome; non-IBS-CON, controls without irritable bowel syndrome; non-IBS-PCOS, polycystic ovary syndrome patients without irritable bowel syndrome; SHBG, sex hormone-binding globulin; TC, total cholesterol; TG, triglycerides; TSH, thyroid-stimulating hormone; T, total testosterone; WC, waist circumference; WHtR, waist-to-height ratio.
Bold indicates statistical significance, P < 0.05.