Figure 1.

circPTPRM was upregulated and miR-139-5p is downregulated in the pulmonary adenocarcinoma tissue samples and cell lines. (a and b) The expression levels of circPTPRM and miR-139-5p were measured by qRT-PCR in the NSCLC patient tissues (n = 26) and the adjacent normal tissues (n = 26). (c) The correlation relationship of circPTPRM with miR-139-5p was analyzed by qRT-PCR in the NSCLC tissues sample. (d and e) The expression levels of circPTPRM and miR-139-5p were assessed by qRT-PCR in pulmonary adenocarcinoma cell lines (eg A549, H1975, and PC-9) and normal human bronchial epithelial 16HBE cells. Data are presented as mean ± SD.

Statistical significant differences were indicated as *P < .05, **P < .01. Abbreviations: circPTPRM: circ RNA PTPRM; qRT-PCR: quantitative real-time polymerase chain reaction.