Cellular uptake of 1a and 1b in HepG-2 and NCI-H460 cells after 12 h of incubationa.
| Complex | Pt contentb (nanograms per 106 cells) | |
|---|---|---|
| HepG-2 | NCI-H460 | |
| Cisplatin | 176 ± 15 | 189 ± 20 |
| Oxaliplatin | 188 ± 12 | 196 ± 19 |
| 1a | 213 ± 17 | 106 ± 17 |
| 1b | 227 ± 26 | 246 ± 31 |
HepG-2 and HCI-H460 cells were treated with 20 μM of cisplatin, oxaliplatin, complexes 1a and 1b for 12 h.
Results are expressed as the mean ± SD for four independent experiments.