. 2022 May 4;23(1):54. doi: 10.1186/s10194-022-01413-z

Table 4.

Mean monthly number of medication prescriptions among persistent (≥ 6 months) patients with a defined dose (n = 746)

	Baseline	Months post-initiation
	Baseline	1	2	3	4	5	6
Acute medication, mean (SD)	1.89 (2.86)	0.57 (0.91)^a	0.22 (0.69)^a	0.25 (0.61)^a	0.31 (1.04)^a	0.24 (0.67)^a	0.25 (0.74)^a
Triptans	0.68 (1.12)	0.30 (0.60)^a	0.08 (0.36)^a	0.09 (0.35)^a	0.11 (0.37)^a	0.10 (0.41)^a	0.08 (0.29)^a
Ergot alkaloids	0.04 (0.41)	0.01 (0.10)^c	0.01 (0.14)^b	0.004 (0.08)^b	0.01 (0.10)^b	0.01 (0.10)^c	0.01 (0.07)^b
NSAID analgesics	0.39 (0.95)	0.08 (0.33)^a	0.03 (0.18)^a	0.04 (0.21)^a	0.05 (0.25)^a	0.03 (0.17)^a	0.05 (0.32)^a
Opioid analgesics	0.56 (2.06)	0.10 (0.49)^a	0.07 (0.34)^a	0.07 (0.31)^a	0.08 (0.58)^a	0.06 (0.39)^a	0.08 (0.42)^a
Preventive nonspecific migraine medication, mean (SD)	2.22 (2.62)	0.58 (0.94)^a	0.30 (0.66)^a	0.34 (0.77)^a	0.33 (0.78)^a	0.27 (0.62)^a	0.31 (0.70)^a
Anticonvulsants/antiepileptics	0.81 (1.36)	0.25 (0.56)^a	0.10 (0.35)^a	0.11 (0.41)^a	0.15 (0.57)^a	0.10 (0.39)^a	0.12 (0.40)^a
Antihypertensive	0.34 (0.82)	0.10 (0.35)^a	0.07 (0.30)^a	0.06 (0.28)^a	0.07 (0.30)^a	0.05 (0.27)^a	0.06 (0.29)^a
Antidepressants	0.62 (1.21)	0.12 (0.37)^a	0.07 (0.30)^a	0.09 (0.39)^a	0.06 (0.27)^a	0.06 (0.27)^a	0.07 (0.29)^a
Botox	0.14 (0.52)	0.03 (0.18)^a	0.02 (0.14)^a	0.03 (0.20)^a	0.01 (0.10)^a	0.01 (0.11)^a	0.02 (0.18)^a

SD standard deviation, NSAID nonsteroidal anti-inflammatory drug

P values calculated via paired t-test against baseline mean

^aP < 0.001

^bP = 0.005

^cP = 0.023