Table 3.
Association of cumulative TyG index with ischemic stroke
| Case/ Total | Incidence rate, per 1000 person-years | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|---|
| Quartiles | |||||
| Q1 | 312/13524 | 2.56 | 1.00 | 1.00 | 1.00 |
| Q2 | 435/13525 | 3.66 | 1.24 (1.07,1.44) | 1.14 (0.98,1.32) | 1.09 (0.94,1.27) |
| Q3 | 604/13525 | 5.24 | 1.53 (1.33,1.76) | 1.34 (1.17,1.55) | 1.26 (1.09,1.45) |
| Q4 | 732/13524 | 6.68 | 1.79 (1.56,2.05) | 1.45 (1.25,1.67) | 1.30 (1.12,1.52) |
| P for Trend | < 0.0001 | < 0.0001 | 0.0002 | ||
| Time exposure duration | |||||
| 0 year | 365/14630 | 2.89 | 1.00 | 1.00 | 1.00 |
| 2 years | 415/12653 | 3.79 | 1.37 (1.19,1.57) | 1.22 (1.06,1.40) | 1.18 (1.02,1.36) |
| 4 years | 501/11733 | 4.95 | 1.77 (1.54,2.02) | 1.42 (1.23,1.63) | 1.32 (1.14,1.54) |
| 6 years | 802/15082 | 6.26 | 2.18 (1.92,2.47) | 1.57 (1.37,1.80) | 1.38 (1.16,1.64) |
| P for Trend | < 0.0001 | < 0.0001 | 0.0003 | ||
Model 1 age (continuous variable, years) and sex (categorical variable, men or women)
Model2: included variables in model 1 and further LDL-C (continuous variable, mmol/L), HDL-C (continuous variable, mmol/L), BMI (continuous variable, kg/m2), hs-CRP (continuous variable, mg/L), smoking status (categorical variable, smoker or non-smoker), alcohol consumption habits (categorical variable, drinker or non-drinker), physical exercise habits (categorical variable, active or inactive), hypertension (categorical variable, yes or no), diabetes mellitus (categorical variable, yes or no), and the use of lipid-lowering drugs (categorical variable, yes or no)
Model 3: included variables in model 2 and further the TyG index (continuous variable) at baseline