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. Author manuscript; available in PMC: 2022 May 3.
Published in final edited form as: J Control Release. 2020 Dec 21;330:329–340. doi: 10.1016/j.jconrel.2020.12.010

Fig. 5.

Fig. 5.

In vitro transfection of ECO/pCMV–ABCA4 and ECO/pCMV–ABCA4–SV40 nanoparticles in ARPE-19 cells demonstrated by qRT-PCR of ABCA4 mRNA expression 48 h after transfections. ABCA4 mRNA expressions were normalized to the expression of ECO/pCMV–ABCA4 at N/P ratio of 6 and 1 μg/mL dose. (*p < 0.05, relative to the mRNA expression of ECO/pCMV–ABCA4 at the same condition. #p < 0.05, relative to the same nanoparticle formulation at 1 μg/mL.)