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. 2022 May 3;21:139. doi: 10.1186/s12936-022-04130-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Evolution of the gene encoding the merozoite surface protein 2. A synteny map of the msp2 region is depicted. A msp2 ortholog is found in the avian parasites’ genomes. A Bayesian phylogeny obtained using MrBayes v3.1.2 on orthologous genes is provided. The branches with the two allelic forms in P. falciparum are colored in red