Box–Behnken design of independent variables and obtained data.

Run	Factor			Extraction yield (mg g−1)
	A	B	C
1	10	50	25	2.00
2	20	60	30	2.33
3	10	60	20	2.18
4	20	50	25	2.18
5	10	70	25	2.28
6	15	60	25	2.28
7	15	70	20	2.25
8	15	60	25	2.28
9	15	70	30	2.38
10	15	60	25	2.25
11	15	60	25	2.29
12	20	70	25	2.34
13	15	50	30	2.04
14	15	60	25	2.27
15	15	50	20	2.05
16	10	60	30	2.28
17	20	60	20	2.31