In vitro antibacterial EC₅₀ activity value of the target compounds against Xac.

Compd	n	R	Toxic regression equationa	r 2	EC50/(μg mL−1)	pEC50/(μM)
6a	3	Ph	y = 0.8044x + 4.1554	0.9961	11.2 ± 3.4	4.8
6b	3	4-CH3-Ph	y = 0.6949x + 4.1397	0.9697	17.3 ± 2.2	4.6
6c	3	3-CH3-Ph	y = 0.8528x + 3.9474	0.9972	17.2 ± 1.4	4.6
6d	3	4-CH3O-Ph	y = 1.0517x + 3.5664	0.9650	23.1 ± 2.8	4.5
6e	3	2-CH3O-Ph	y = 0.6924x + 3.7991	0.9822	54.3 ± 2.4	4.1
6f	3	3,4-Di-CH3-Ph	y = 0.8130x + 4.1875	0.9977	10.0 ± 3.9	4.8
6g	3	3,4-Di-CH3O-Ph	y = 0.9169x + 3.8298	0.9762	18.9 ± 2.6	4.6
6h	3	2,4-Di-CH3O-Ph	y = 0.6912x + 3.8298	0.9690	28.1 ± 1.5	4.4
6i	3	4-t-Bu-Ph	y = 0.7819x + 4.2398	0.9917	9.4 ± 1.9	4.9
6j	3	2-Thiophene	y = 0.9335x + 3.8960	0.9642	15.2 ± 2.9	4.6
6k	4	Ph	y = 0.9655x + 3.7731	0.9334	18.7 ± 0.8	4.6
6l	4	4-CH3-Ph	y = 0.9335x + 4.0630	0.9877	10.1 ± 1.1	4.8
6m	4	3-CH3-Ph	y = 0.7733x + 4.0122	0.9599	18.9 ± 0.9	4.6
6n	4	4-CH3O-Ph	y = 0.9324x + 3.9636	0.9716	12.9 ± 1.9	4.7
6o	4	2-CH3O-Ph	y = 0.6712x + 4.1730	0.9624	17.1 ± 2.5	4.6
6p	4	3,4-Di-CH3-Ph	y = 0.9633x + 3.8184	0.9729	16.9 ± 2.6	4.6
6q	4	3,4-Di-CH3O-Ph	y = 0.9311x + 4.1191	0.9819	8.8 ± 1.9	4.9
6r	4	2,4-Di-CH3O-Ph	y = 0.5861x + 4.1558	0.9706	27.6 ± 3.1	4.4
6s	4	4-t-Bu-Ph	y = 0.7906x + 4.0584	0.9903	15.5 ± 2.0	4.7
6t	5	Ph	y = 1.1883x + 3.6956	0.9958	12.5 ± 2.9	4.7
6u	5	4-CH3-Ph	y = 0.7831x + 3.9652	0.9780	21.0 ± 1.0	4.5
6v	5	4-CH3O-Ph	y = 0.7105x + 4.0749	0.9998	20.5 ± 2.7	4.5
6w	5	3,4-Di-CH3O-Ph	y = 0.7706x + 4.0642	0.9814	16.4 ± 1.9	4.7
Myrb	—	—	y = 0.6520x + 3.6763	0.9838	107.2 ± 1.6	—
BTc	—	—	y = 0.8357x + 3.5466	0.9876	54.9 ± 1.4	—
TCc	—	—	y = 0.8874x + 3.4149	0.9984	61.1 ± 3.4	—

^aTested and calculated at the drug test concentrations of 100, 50, 25, 12.5, and 6.25 μg mL⁻¹.

^bMyr (myricetin).

^cBT (commercial fungicides, bismerthiazol) and TC (thiediazole copper).