Table 3.
Adjusted outcomes stratified by cardiac intensive care unit mechanical ventilation volumes in the overall cohort and hospital subtypes
| Outcomes | Group 1 | Group 2 | Group 3 |
|---|---|---|---|
| Annual volume ≤100 | Annual volume 101–300 | Annual volume >300 | |
| Mortality | Adjusted OR (95 % CI) | Adjusted OR (95% CI) | Adjusted OR (95% CI) |
| Overall cohort | Ref | 0.84 (0.72–0.97), P = 0.019 | 0.82 (0.66–1.02), P = 0.076 |
| Academic | Ref | 0.81 (0.67–0.97), P = 0.023 | 0.80 (0.62–1.04), P = 0.10 |
| Community | Ref | 0.99 (0.85–1.16), P = 0.93 | a |
| PCI-capable | Ref | 0.80 (0.67–0.97), P = 0.019 | 0.79 (0.62–1.01), P = 0.064 |
| Non PCI-capable | Ref | 0.92 (0.74–1.34), P = 0.42 | a |
| Prolonged MV (>96 h) | Adjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Overall cohort | Ref | 0.85 (0.68–1.06), P = 0.14 | 0.70 (0.55–0.89), P = 0.003 |
| Academic | Ref | 0.80 (0.63–1.03), P = 0.084 | 0.66 (0.52–0.84), P = 0.001 |
| Community | Ref | 0.93 (0.64–1.34), P = 0.68 | a |
| PCI-capable | Ref | 0.69 (0.58–0.82), P < 0.001 | 0.58 (0.48–0.71), P < 0.001 |
| Non PCI-capable | Ref | 1.35 (0.90–2.04), P = 0.15 | a |
| CICU LOS, h | Adjusted risk difference (95% CI) | Adjusted risk difference (95% CI) | |
| Overall cohort | Ref | −9.69 (−28.27, 8.88), P = 0.31 | −10.42 (−30.54, 9.70), P = 0.31 |
| Academic | Ref | −18.37 (−39.23, 2.49), P = 0.084 | −18.73 (−41.50, 4.05), P = 0.11 |
| Community | Ref | 6.42 (−27.54, 40.37), P = 0.71 | a |
| PCI-capable | Ref | −25.44 (−38.21, −12.66), P < 0.001 | −25.18 (−42.84, −7.51), P = 0.005 |
| Non PCI-capable | Ref | 32.75 (−7.18, 72.67), P = 0.11 | a |
| Hospital LOS, h | Adjusted risk difference (95% CI) | Adjusted risk difference (95% CI) | |
| Overall cohort | Ref | −0.87 (−2.71, 0.97), P = 0.36 | −2.30 (−5.39, 0.78), P = 0.14 |
| Academic | Ref | −1.35 (−3.36, 0.66), P = 0.19 | −2.72 (−5.93, 0.48), P = 0.096 |
| Community | Ref | 0.04 (−3.26, 3.35), P = 0.98 | a |
| PCI-capable | Ref | −1.56 (−3.44, 0.32), P = 0.10 | −2.88 (−5.95, 0.19), P = 0.066 |
| Non PCI-capable | Ref | 1.20 (−1.97, 4.37), P = 0.46 | a |
Adjusted for age, sex, diabetes, hypertension, heart failure, myocardial infarction, atrial fibrillation, cerebrovascular disease, peripheral vascular disease, renal disease, cancer, dementia, admission category (emergency department vs. transferred), discharge diagnosis-valvular heart disease, heart failure and cardiomyopathies, arrhythmia, conduction disorder, pericardial disease, aortic and arterial disease, shock, and critical care therapy-resuscitation, dialysis, catheterization or PCI, and MV type (invasive and non-invasive).
CI, confidence interval; CICU, cardiac intensive care unit; LOS, length of stay; MV, mechanical ventilation; OR, odds ratio; PCI, percutaneous coronary intervention; ref, reference group.
There were no community or non-PCI capable hospitals in the high-volume group.