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. 2022 May 1;14(1):2056944. doi: 10.1080/19420862.2022.2056944

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Observed and modeled relationship between FcRn $K_{d}^{6.0}$ and FcRn relative retention time (hFcRn_RT). The dots represent available assay results of 37 antibodies.⁵ The line indicates the nonlinear regression relationship: $K_{d}^{6.0} = 1136 \cdot e^{- 0.52 \cdot h F c R n_R T}$ , R = 0.79.

ALT Text: A scatter plot with 37 points and a decaying fitting curve. Most points locate around the curve with four points away from it. The x axis is labeled with hFcRn_RT with a range of 0.0 to 10.0. The y axis has a title of “FcRn K_d^6.0 (nM)” ranging from 0 to 2000.