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. 2022 May 2;16(1):97–112. doi: 10.1080/19336950.2022.2055521

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Metoprolol does not modify APD or CaT alternans. V_m and [Ca]_i traces from atrial myocytes in control (A) and during metoprolol (10 µM) treatment (B). APs and CaTs were elicited by field stimulation at 2 Hz. C, Mean APD50 of long (L; control vs. metoprolol: P = 0.35, n = 11) and short (S; P = 0.21) APs during alternans (panel a) and average AR_APD50 (panel b) in control and metoprolol (Met; P = 0.37, n = 11). D, average CaT amplitudes of large (L: control vs. metoprolol, P = 0.43) and small (S; P = 0.29) amplitude alternans CaTs (panel a) and average CaT AR (panel b) in control and metoprolol (P = 0.41). Statistical analysis with unpaired t-test.