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. 2022 May 4;22:177. doi: 10.1186/s12890-022-01966-4

Table 2.

Comparison of biopsy specimens, safety, diagnosis, and prognosis between the patients underwent TBLB and TBLC

TBLB (n = 45) TBLC (n = 25) p value
Specimen (Median, IQR)
Number 4 (2–6) 4 (3–5) 0.380
Length diameter, mm 1.0 (0.5–2.0) 5.3 (4.8–5.6)  < 0.001
Short diameter, mm 0.5 (0.5–0.8) 3.7 (3.3–4.3)  < 0.001
Artifacts (n, %)
Crash/atelectasis 25 (55.6) 0  < 0.001
Traumatic bleeding 4 (8.9) 4 (16.0) 0.443
Non-alveolar tissue 8 (17.8) 0 0.044
Complications (n, %) 7 (15.6) 7 (28.0) 0.212
Moderate bleeding 0 7 (28.0)  < 0.001
Severe bleeding 0 0
Pneumothorax 6 (13.3) 0 0.056
Others 1 (2.2) 0 1.000
ΔAPACHE II score ≥ 5 (n, %) 0 4 (16.0) 0.006
ΔSOFA score ≥ 3 (n, %) 1 (2.2) 4 (16.0) 0.032
Pathological diagnosis (n, %) 17 (37.8) 18 (72.0) 0.006
MDD diagnosis (n, %) 25 (55.6) 21 (84.0) 0.016
Treatment modifications (n, %) 26 (57.8) 21 (84.0) 0.025
28-day survival (n, %) 25 (55.6) 16 (64.0) 0.492

APACHE II score, acute physiology and chronic health evaluation II score; SOFA score, sequential organ failure assessment score; MDD, Multidisciplinary discussion

Bold for statistically significant (p value < 0.05)