Table 6. Statistical analysis of data shown in Fig 5B and 5C for place reversal, cohort A, Run-1, and Run-2.

Fig 5B and 5C	Two-way RM ANOVA
Run-1	Source of Variation	F (DFn, DFd)	P
	Interaction	F (2, 44) = 0.08855	0.9154
	Day factor(5B)	F (2, 44) = 12.26	<0.0001
	Sex factor(5C)	F (1, 22) = 15.38	0.0007
	post-hoc Sidak’s multiple comp. test	Summary	Adjusted P
	Female, day 1 vs. day 2	*	0.0277
	Female, day 1 vs. day 3	**	0.0020
	Female, day 2 vs. day 3	ns	0.7307
	Male, day 1 vs. day 2	ns	0.0713
	Male, day 1 vs. day 3	*	0.0109
	Male, day 2 vs. day 3	ns	0.8461
	Female vs. Male, day 1	**	0.0042
	Female vs. Male, day 2	**	0.0100
	Female vs. Male, day 3	*	0.0153
Run-12	Source of Variation	F (DFn, DFd)	P
	Interaction	F (2, 38) = 0.4885	0.6174
	Day factor(5B)	F (2, 38) = 4.223	0.0221
	Sex factor(5C)	F (1, 19) = 0.02749	0.8701
	post-hoc Sidak’s multiple comp. test	Summary	Adjusted P
	Female, day 1 vs. day 2	ns	0.8887
	Female, day 1 vs. day 3	ns	0.2396
	Female, day 2 vs. day 3	ns	0.6212
	Male, day 1 vs. day 2	ns	0.1257
	Male, day 1 vs. day 3	ns	0.0804
	Male, day 2 vs. day 3	ns	0.9957

A p-value less than 0.05 is considered significant (*p < 0.05, **p < 0.01). ns = not significant.