Table 16. Statistical analysis of data shown in Fig 10A and 10B for serial reversal, cohort B, Run-1, and Run-2.

Fig 10A and 10B	Mixed-effects analysis
Correct Run-1	Source of Variation	F (DFn, DFd)	P
	Interaction	F (3, 49) = 1.404	0.2527
	Day factor(10A)	F (3, 49) = 0.4026	0.7518
	Sex factor(10B)	F (1, 18) = 0.2942	0.5942
Correct Run-2	Source of Variation	F (DFn, DFd)	P
	Interaction	F (3, 54) = 1.273	0.2928
	Day factor(10A)	F (3, 54) = 1.481	0.2300
	Sex factor(10B)	F (1, 18) = 61.77	<0.0001
	post-hoc Sidak’s multiple comp. test	Summary	Adjusted P
	Female vs. Male, day 1	****	<0.0001
	Female vs. Male, day 2	****	<0.0001
	Female vs. Male, day 3	****	<0.0001
	Female vs. Male, day 4	****	<0.0001
Opposite Run-1	Source of Variation	F (DFn, DFd)	P
	Interaction	F (3, 49) = 0.1940	0.9000
	Day factor(10A)	F (3, 49) = 0.7972	0.5014
	Sex factor(10B)	F (1, 18) = 0.7083	0.4111
Opposite Run-2	Source of Variation	F (DFn, DFd)	P
	Interaction	F (3, 54) = 0.6292	0.5993
	Day factor(10A)	F (3, 54) = 0.05791	0.9815
	Sex factor(10B)	F (1, 18) = 18.17	0.0005
	post-hoc Sidak’s multiple comp. test	Summary	Adjusted P
	Female vs. Male, day 3	*	0.0242
	Female vs. Male, day 4	**	0.0056

(*p < 0.05, **p < 0.01, ****p < 0.0001). A p-value less than 0.05 is considered significant.