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. 2022 May 4;17(5):e0267584. doi: 10.1371/journal.pone.0267584

Table 3. Factors associated with the mortality in COVID-19 with recent cancer.

  Crude RR p-value adjusted RR p-value
Cancer Treatment
    Chemo within 3-month before COVID-19 1.31 (1.08–1.60) 0.006 1.37 (1.12–1.69) 0.003
    Radiation within 3-month before COVID-19 1.89 (1.44–2.49) <0.001 1.83 (1.37–2.46) <0.001
Age group
    <45 1 (reference)
    45–54 1.41 (0.66–2.99) 0.37 1.21 (0.57–2.57) 0.62
    55–64 3.18 (1.66–6.09) <0.001 2.28 (1.19–4.37) 0.013
    65–74 6.29 (3.35–11.83) <0.001 3.50 (1.83–6.69) <0.001
    75+ 14.41 (7.73–26.83) <0.001 6.69 (3.50–12.78) <0.001
Male 1.63 (1.47–1.82) <0.001 1.12 (0.98–1.28) 0.106
Race/ethnicity
    White 1 (reference)
    Black 1.26 (1.03–1.54) 0.027 1.25 (1.02–1.53) 0.029
    Hispanic 0.67 (0.49–0.92) 0.014 0.93 (0.68–1.28) 0.65
    Other/unknown 0.82 (0.56–1.20) 0.31 1.08 (0.74–1.58) 0.704
Insurance Type
    Commercial 1 (reference)
    Medicare 2.37 (2.05–2.74) <0.001 1.29 (1.11–1.51) 0.001
    Medicaid 0.87 (0.57–1.32) 0.51 1.37 (0.89–2.10) 0.154
    Uninsured 0.53 (0.20–1.40) 0.20 0.73 (0.28–1.88) 0.51
    Other 1.45 (0.99–2.12) 0.057 1.40 (0.98–2.01) 0.066
    Unknown 1.14 (0.70–1.86) 0.602 1.24 (0.77–2.00) 0.38
Region
    Northeast 1 (reference)
    Midwest 1.03 (0.85–1.26) 0.73 1.07 (0.88–1.30) 0.507
    South 1.70 (1.38–2.10) <0.001 1.64 (1.33–2.03) <0.001
    West 1.17 (0.85–1.61) 0.335 1.22 (0.89–1.68) 0.208
    Other/Unknown 1.29 (0.80–2.07) 0.294 1.19 (0.76–1.88) 0.444
Risk Factors
    Chronic Pulmonary Disease 1.42 (1.24–1.63) <0.001 0.96 (0.84–1.10) 0.56
    Cardiovascular Disease 3.50 (2.97–4.13) <0.001 1.72 (1.43–2.07) <0.001
    Cerebrovascular Disease 1.98 (1.71–2.28) <0.001 1.09 (0.94–1.26) 0.28
    Peripheral Vascular Disease 2.01 (1.75–2.30) <0.001 1.03 (0.89–1.19) 0.69
    Diabetes 2.04 (1.79–2.34) <0.001 1.39 (1.20–1.60) <0.001
    Obesity 0.96 (0.84–1.10) 0.571 0.86 (0.75–0.99) 0.039
    Liver Disease 1.23 (1.06–1.43) 0.008 1.16 (1.00–1.36) 0.05
    Renal Disease 2.80 (2.45–3.20) <0.001 1.51 (1.31–1.75) <0.001