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. 2022 May 2;29(1):1326–1334. doi: 10.1080/10717544.2022.2069301

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Schematic of experimental setup for in vitro evaluation of ranibizumab release from the PDS implant. To enable in vitro evaluation of drug release, PDS implants were filled with ranibizumab solution and individually suspended on custom-designed hangers, placed in 1.5-mL polypropylene tubes containing 300 µL of release buffer. Implants were transferred to new polypropylene tubes with fresh buffer at regular intervals to maintain sink conditions for ranibizumab release. Abbreviation: PDS: Port Delivery System with ranibizumab. Yohe S, Maass KF, Horvath J, Rea J, Barteselli G, Ranade SV. J Control Release. 2022;345:101–107. Licensed under CC-BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/).