Table 1.
Compound no. | Structure | Yield % | Cytotoxicity IC50 µM |
---|---|---|---|
A549 cells | |||
3a (Sunifiram) (DM235) | 93 | 85.93 ± 4.43 | |
3b | 86 | Not applied | |
3c | 91 | 101.5 ± 5.24 | |
3d | 91 | 49.26 ± 2.54 | |
3e | 92 | 52.77 ± 2.72 | |
3f | 93 | 32.17 ± 1.66 | |
3g | 89 | 37.98 ± 1.96 | |
3h | 84 | 43.49 ± 2.24 | |
3i | 87 | 96.63 ± 4.98 | |
3j | 81 | 57.51 ± 2.97 |