Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 26;44(1):694–705. doi: 10.1080/0886022X.2022.2063744

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — The expression of VDR protein and autophagosomes is down-regulated in diabetic kidneys. (A) The VDR level was detected by immunohistochemical staining (×400). (B) Representative pictures of anti-beclin1 immunohistochemical staining (×400). (C) Kidney biopsy specimens were from patients with diabetic nephropathy (DN) and non-tumor renal tissue from patients with kidney cancer. Representative ultrastructural imagines showing the double-membraned vesicles (autophagosomes) in podocytes. Basement membrane (red arrows) and autophagosomes (yellow arrow). (D) Western blot analysis of VDR and Beclin1 in the renal cortex of rats from each group as indicated. (E) Relative expression of proteins levels. (F) The VDR levels in patients with diabetic nephropathy (DN) and non-tumor renal tissue from patients with kidney cancer were measured by ELISA. Data were presented as mean ± SD. ***p < 0.001.