Table 2.
Embryo transfer outcomes
| Outcome | PRP cycles | Previous cycles | Risk ratio (95% CI) |
p-value |
|---|---|---|---|---|
| Complete population | n = 116 | n = 187 | ||
| Biochemical pregnancy | 56 (48.3%) | 72 (35.5%) | 1.25 (1.03–1.55) | 0.03 |
| Clinical pregnancy | 43 (37.1%) | 41 (20.2%) | 1.27 (1.10–1.50) | < 0.01 |
| Spontaneous abortion | 34 (60.7%) | 68 (94.4%) | 0.43 (0.16–1.07) | 0.09 |
| Live birth | 22 (19.0%) | 4 (2.0%) | 1.21 (1.12–1.35) | < 0.01 |
| Thin endometrium | n = 31 | n = 18 | ||
| Biochemical pregnancy | 16 (51.6%) | 18 (52.9%) | 1.03 (0.61–1.72) | > 0.99 |
| Clinical pregnancy | 9 (29.0%) | 9 (26.5%) | 1.04 (0.76–1.44) | > 0.99 |
| Spontaneous abortion | 11 (68.8%) | 17 (94.4%) | 0.18 (0.03–1.00) | 0.08 |
| Live birth | 5 (16.1%) | 1 (5.6%) | 1.13 (0.89–1.42) | 0.38 |
| Recurrent implantation failure | n = 61 | n = 141 | ||
| Biochemical pregnancy | 31 (50.8%) | 48 (34.0%) | 1.34 (1.04–1.82) | 0.03 |
| Clinical pregnancy | 27 (44.3%) | 29 (20.6%) | 1.43 (1.15–1.86) | < 0.01 |
| Spontaneous abortion | 17 (54.8%) | 45 (93.8%) | 0.14 (0.05–0.41) | < 0.01 |
| Live birth | 14 (23%) | 3 (2.1%) | 1.27 (1.14–1.51) | < 0.01 |
| Recurrent implantation failure and thin endometrium | n = 24 | n = 28 | ||
| Biochemical pregnancy | 9 (37.5%) | 6 (21.4%) | 1.26 (0.88–1.90) | 0.23 |
| Clinical pregnancy | 7 (29.2%) | 3 (10.7%) | 1.26 (0.96–1.78) | 0.15 |
| Spontaneous abortion | 6 (66.7%) | 6 (100%) | 0 (0–1.47) | 0.22 |
| Live birth | 3 (19.0%) | 0 (0.0%) | ∞ (1.06–∞) | 0.09 |
n = number of embryo transfers. The total number of embryo transfers is less than the number of PRP cycles due to cancelled cycles (inadequate endometrial growth, COVID-19 exposures). Biochemical pregnancy rates are calculated as a percentage of single embryo transfers, while the other outcome rates are calculated as the percentage of biochemical pregnancies